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Dr. Eli Rothenberg,  Principal Investigator 

 

Research: A bit of everything…

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Dr. Dipika Gupta, Postdoctoral Fellow
 
Research:
  • Mechanisms of replication fork remodeling, protection and repair.  
  • Single-molecule imaging of replication fork reversal and restart.
  • Drug induced synthetic lethality in cancer.
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Dr. Huijun Xue, Postdoctoral Fellow
 
Research:
  • Dynamics of DSBs repair and pathway choice in live cells.
  • PARP inhibitors Mechanism of Action.
  • Development of new single-molecule assays for monitoring PARP1 activity . 
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Dr. Carolus Fijen, Postdoctoral Fellow
 
Research:
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  • Single-molecule biochemical studies of the human DNA polymerase theta (polq).
     
  • STORM microscopy and single-molecule tracking  of DSB repair complexes ultrastructure and the dynamics of TMEJ pathway.  
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Dr. Shaun Christie, Postdoctoral Fellow
 
Research:
  • Cellular studies of V(D)J recombination and immunodeficiencies using single-molecule imaging.
  • Development of high throughput live-cell single-molecule imaging platforms.
  • Cellular studies of Drug delivery 
  • Studies of virus cell-membrane interactions 
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Dr. Sagun Jonchhe, Postdoctoral Fellow
 
Research:
 
  • Single-molecule biochemical studies of the human NHEJ complexes repair.
     
  • Cellular imaging of DSB repair dynamics.

    Development of new single-molecule biochemical functional assays for DNA repair proteins. 
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Anastasiya Ephstein, Research Tech
 
Research:
Engineering novel mammalian cell lines and biomarkers for monitoring DNA Repair  
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Dr. George Hamilton, Postdoctoral Fellow
 
Research:
  • Single-molecule biochemical studies of V(D)J recombination and the activity of human RAG proteins and crosstalk with NHEJ .
  • Cellular imaging of replication fork dynamics.
  • Development of new single-molecule platforms for high-throughput studies.
Dr. Sudipta Lahiri, Postdoctoral Fellow
 
Research:

  • Single-molecule biochemical and cellular studies of human mutations in HR proteins in Ovarian and Breast Cancer.
  • Consequences of BRCA2 and BRCA1 mutations in DNA repair  
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Dr. Shao-Kuei Huang, Research Scientist
 
Research:
  • Single-molecule imaging of RNA transaction and dynamics in cells.
  • Development of new imaging approaches and assays for localization microscopy on chromosomes.
     
Alumni and Visitors ::

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Beth Woodward

Wentao Lee

Grace Tang

Yandong Yin

WeiTing Chelsea Lee

Michael Morten

Donna Whelan

Claudia Gonzales Leal

Aina Maria Mas Calafell

Pam Pam Gwo

Dylan Ofri

Frances Marks

Jaewoo Shin

Dylan Reid

Tina Kong

Esperanza Agullo-Pascual

Alejandra Leo-Macias

Sarah Vermij

Jen Zagelbaum

Sujoy Chatterjee

Carissa Meyer

Kate Kaiser

Syed Sarder

Estie Schick

Simone Persampieri

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