PUBLICATIONS

2023

Stepwise requirements for polymerases δ and θ in theta-mediated end joining.

Stroik S, Carvajal-Garcia J, Gupta D, Edwards A, Luthman A, Wyatt DW, Dannenberg RL, Feng W, Kunkel TA, Gupta GP, Hedglin M, Wood R, Doublié S, Rothenberg E, Ramsden DA.

Nature 623(7988):836-841 (2023).

Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.

Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J, Rak A, Legrand P, Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E, Britton S, Calsou P, Blundell TL, Varela PF, Chaplin AK, Charbonnier JB.

Nucleic Acids Res. 51(21):11732-11747. (2023).

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins.

Mas AM, Goñi E, Ruiz de Los Mozos I, Arcas A, Statello L, González J, Blázquez L, Lee WTC, Gupta D, Sejas Á, Hoshina S, Armaos A, Tartaglia GG, Waga S, Ule J, Rothenberg E, Gómez M, Huarte M.

Nature Communications 14(1):4447 (2023).

Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram.

Svetlana Maurya, Robert W. Mills, Konstantin Kahnert, David Y. Chiang, Giorgia Bertoli, Pia R. Lundegaard, Marta Perez-Hernandez Duran, Mingliang Zhang, Eli Rothenberg, Alfred L. George Jr., Calum A. MacRae, Mario Delmar & Alicia Lundby.

Nature Cardiovascular Research. 2(7):673-692 (2023).

2022

Single virus tracking reveals variant SARS-CoV-2 spike proteins induce ACE2-independent membrane interactions.

Christie SM, Tada T, Yin Y, Bhardwaj A, Landau NR, Rothenberg E.

Science Advances 8: eabo397 (2022).

The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells.

Vipat S, Gupta D, Jonchhe S, Anderspuk H, Rothenberg E, Moiseeva TN.

Nature Communications 13(1):7099 (2022).

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair.

Jimenez-Sainz J, Mathew J, Moore G, Lahiri S, Garbarino J, Eder JP, Rothenberg E, Jensen RB.

eLIFE 11:e79183 (2022).

A two-step mechanism governing PARP1-DNA retention by PARP inhibitors.

Xue H, Bhardwaj A, Yin Y, Fijen C, Ephstein A, Zhang L, Ding X, Pascal JM, VanArsdale TL, Rothenberg E.

Science Advances 8(36):eabq0414 (2022).

Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC.

Pérez-Hernández M, van Opbergen CJM, Bagwan N, Vissing CR, Marrón-Liñares GM, Zhang M, Torres Vega E, Sorrentino A, Drici L, Sulek K, Zhai R, Hansen FB, Christensen AH, Boesgaard S, Gustafsson F, Rossing K, Small EM, Davies MJ, Rothenberg E, Sato PY, Cerrone M, Jensen THL, Qvortrup K, Bundgaard H, Delmar M, Lundby A.

Circulation 146(11):851-867 (2022).

V(D)J Recombination: Recent Insights in Formation of the Recombinase Complex and Recruitment of DNA Repair Machinery.

Christie SM, Fijen C, Rothenberg E.

Front Cell Dev Biol 10:886718 (2022).

Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression.

Zheng J, Dooge HC, Pérez-Hernández M, Zhao YT, Chen X, Hernandez JJ, Valdivia CR, Palomeque J, Rothenberg E, Delmar M, Valdivia HH, Alvarado FJ.

J Mol Cell Cardiol. 167:118-128 (2022).

USP1-trapping lesions as a source of DNA replication stress and genomic instability.

Coleman KE, Yin Y, Lui SKL, Keegan S, Fenyo D, Smith DJ, Rothenberg E, Huang TT.

Nature Communications 13(1):1740 (2022).

2021

Single-molecule imaging of replication fork conflicts at genomic DNA G4 structures in human cells.

Lee WTC, Gupta D, Rothenberg E.

Methods in Enzymology 661:77-94 (2021).

A basal-level activity of ATR links replication fork surveillance and stress response.

Yin Y, Lee WTC, Gupta D, Xue H, Tonzi P, Borowiec JA, Huang TT, Modesti M, Rothenberg E.

Molecular Cell 81(20):4243-4257 (2021).

The evolving complexity of DNA damage foci: RNA, condensates and chromatin in DNA double-strand break repair.

Fijen C, Rothenberg E.

DNA Repair 105:103170. (2021).

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.

Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Turchi JJ, Johnson N, Jonkers J, Rothenberg E, Cantor SB

Molecular Cell 81(15):3128-3144 (2021).

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer.

Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, Li F, Li S, Ding H, Hu H, Pan Y, Weerasekara V, Jiang B, Wang ES, Ahearn I, Philips M, Papagiannakopoulos T, Tsirigos A, Rothenberg E, Gainor J, Freeman GJ, Rudin CM, Gray NS, Hammerman PS, Pagano M, Heymach JV, Perou CM, Bardeesy N, Wong KK

Nature Cancer 2(5):503-514 (2021).

Targeting the Microtubule EB1-CLASP2 Complex Modulates Na V 1.5 at Intercalated Discs.

Marchal GA, Jouni M, Chiang DY, Pérez-Hernández M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George AL Jr, Verkerk AO, Bezzina CR, MacRae CA, Burridge PW, Delmar M, Galjart N, Portero V, Remme CA.

Circulation Research 29(3):349-365 (2021).

Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling.

Lee WTC, Yin Y, Morten MJ, Tonzi P, Gwo PP, Odermatt DC, Modesti M, Cantor SB, Gari K, Huang TT, Rothenberg E.

Nature Communications 12(1):2525 (2021).

Understanding DNA organization, damage, and repair with super-resolution fluorescence microscopy.

Miriklis EL, Rozario AM, Rothenberg E, Bell TDM, Whelan DR.

Methods Appl Fluoresc. May 5;9(3) (2021).

Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability.

De Smet MA, Lissoni A, Nezlobinsky T, Wang N, Dries E, Pérez-Hernández M, Lin X, Amoni M, Vervliet T, Witschas K, Rothenberg E, Bultynck G, Schulz R, Panfilov AV, Delmar M, Sipido KR, Leybaert L.

J Clin Invest. 131(7):e137752 (2021).

Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination.

Whelan DR, Rothenberg E.

PNAS 118(11):e2021963118 (2021).

MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.

Sharma S, Anand R, Zhang X, Francia S, Michelini F, Galbiati A, Williams H, Ronato DA, Masson JY,

Rothenberg E, Cejka P, d’Adda di Fagagna F.

Cell Reports. 34, 108565 (2021).

Super-Resolution Imaging of Homologous Recombination Repair at Collapsed Replication Forks.

Whelan DR, Rothenberg E.

Methods in Molecular Biology. 2153:355-363 (2021).

Structural and Functional Characterization of a Nav1.5-Mitochondrial Couplon.

Pérez-Hernández M, Leo-Macias A, Keegan S, Jouni M, Kim JC, Agullo-Pascual E, Vermij S, Zhang M, Liang FX, Burridge P, Fenyo D, Rothenberg E, Delmar M.

Circulation Research. 128(3):419-432 (2021).

2020

Super-Resolution Visualization of Distinct Stalled and Broken Replication Fork Structures.
Whelan DR, Lee WTC, Marks F, Kong YT, Yin Y, Rothenberg E.

PLoS Genet 16(12):e1009256 (2020).

Single-Molecule Fluorescence Imaging Techniques.

Morten MJ, Reid DA, Rothenberg E.

Encyclopedia of Analytical Chemistry eds R.A. Meyers, John Wiley: Chichester. (2020).

DOI: 10.1002/9780470027318.a9494.pub2.

The Molecular Basis and Disease Relevance of Non-Homologous DNA End Joining.
Zhao B, Rothenberg E, Ramsden DA, Lieber MR.

Nature Reviews Mol Cell Biol. 21,765–781 (2020).

Genome-Wide Alterations of Uracil Distribution Patterns in Human DNA upon Chemotherapeutic Treatments.

Pálinkás HL, Békési A, Róna G, Pongor L, Papp G, Tihanyi G, Holub E, Póti Á, Gemma C, Ali S, Morten MJ, Rothenberg E, Pagano M, Szűts D, Győrffy B, Vértessy BG.

eLIFE 9:e60498 (2020).

Cancer-Associated Mutations in the Iron-Sulfur Domain of FANCJ Affect G-Quadruplex Metabolism.

Odermatt DC, Lee WTC, Wild S, Jozwiakowski SK, Rothenberg E, Gari K.

PLoS Genet 16(6):e1008740 (2020).

Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains.

Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H.

Circ Arrhythm Electrophysiol 13(7):e008241 (2020).

Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters.

Trcek T, Douglas TE, Grosch M, Yin Y, Eagle WVI, Gavis ER, Shroff H, Rothenberg E, Lehmann R.

Molecular Cell 78(5):941-950.e12 21, (2020).

Preserving Genome Integrity in Human Cells via DNA Double-Strand Break Repair.
Jensen RB, Rothenberg E.
Molecular Biology of the Cell 31(9):859-865 (2020).

Ankyrin-G Mediates Targeting of both Na+ and KATP Channels to the Rat Cardiac Intercalated Disc.
Yang HQ, Pérez-Hernández M, Sanchez-Alonso J, Shevchuk A, Gorelik J, Rothenberg E, Delmar M, Coetzee WA.
eLIFE 9:e52373 (2020).

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Zhang H, Christensen CL, Dries R, Oser MG, Deng J, Diskin B, Li F, Pan Y, Zhang X, Yin Y, Papadopoulos E, Pyon V, Thakurdin C, Kwiatkowski N, Jani K, Rabin AR, Castro DM, Chen T, Silver H, Huang Q, Bulatovic M, Dowling CM, Sundberg B, Leggett A, Ranieri M, Han H, Li S, Yang A, Labbe KE, Almonte C, Sviderskiy VO, Quinn M, Donaghue J, Wang ES, Zhang T, He Z, Velcheti V, Hammerman PS, Freeman GJ, Bonneau R, Kaelin WG Jr, Sutherland KD, Kersbergen A, Aguirre AJ, Yuan GC, Rothenberg E, Miller G, Gray NS, Wong KK.
Cancer Cell 37(1):37-54.e9 (2020).

2019

KRAS4A Directly Regulates Hexokinase 1.
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, Balmain A, Kimmelman AC, Philips MR.
Nature 576(7787):482-486 (2019).

Functional Transcription Promoters at DNA Double-Strand Breaks Mediate RNA-Driven Phase Separation of Damage-Response Factors.
Pessina F, Giavazzi F, Yin Y, Gioia U, Vitelli V, Galbiati A, Barozzi S, Garre M, Oldani A, Flaus A, Cerbino R, Parazzoli D, Rothenberg E, d'Adda di Fagagna F.

Nature Cell Biology 21(10):1286-1299 (2019).

The Essential Elements for the Noncovalent Association of Two DNA Ends During NHEJ Synapsis.

Zhao B, Watanabe G, Morten MJ, Reid DA, Rothenberg E, Lieber MR.

Nature Communications 10(1):3588 (2019).

Disruption of Ca2+ Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice.

Kim JC, Pérez-Hernández M, Alvarado FJ, Maurya SR, Montnach J, Yin Y, Zhang M, Lin X, Vasquez C, Heguy A, Liang FX, Woo SH, Morley GE, Rothenberg E, Lundby A, Valdivia HH, Cerrone M, Delmar M.

Circulation 140(12):1015-1030 (2019).

An ATR and CHK1 Kinase Signaling Mechanism that Limits Origin Firing During Unperturbed DNA Replication.

Moiseeva TN, Yin Y, Calderon MJ, Qian C, Schamus-Haynes S, Sugitani N, Osmanbeyoglu HU, Rothenberg E,
Watkins SC, Bakkenist CJ.

PNAS 116(27):13374-13383 (2019).

Ultrafast Data Mining of Molecular Assemblies in Multiplexed High-Density Super-Resolution Images.

Yandong Yin, Wei Ting Chelsea Lee, and Eli Rothenberg.

Nature Communications 10(1):119 (2019).

2018

Guidelines for DNA Recombination and Repair Studies: Mechanistic Assays of DNA Repair Processes.

Hannah L Klein, Kenny K.H. Ang, Michelle R. Arkin, Emily C. Beckwitt, Yi-Hsuan Chang, Jun Fan, Youngho Kwon, Michael J. Morten, Sucheta Mukherjee, Oliver J. Pambos, Hafez el Sayyed, Elizabeth S. Thrall, João P. Vieira-da-Rocha, Quan Wang, Shuang Wang, Hsin-Yi Yeh, Julie S. Biteen, Peter Chi, Wolf-Dietrich Heyer, Achillefs N. Kapanidis, Joseph J. Loparo, Terence R. Strick, Patrick Sung, Bennett Van Houten, Hengyao Niu, and Eli Rothenberg.

Microbial Cell 6(1):65-101 (2018).

BRCA2 controls DNA: RNA hybrid level at DSBs by mediating RNase H2 recruitment.

Giuseppina D’Alessandro, Donna Rose Whelan, Sean Michael Howard, Valerio Vitelli, Xavier Renaudin, Marek Adamowicz, Fabio Iannelli, Corey Winston Jones-Weinert, MiYoung Lee, Valentina Matti, Wei Ting C. Lee, Michael John Morten, Ashok Raraakrishnan Venkitaraman, Petr Cejka, Eli Rothenberg and Fabrizio d’Adda di Fagagna.

Nature Communications 9(1):5376 (2018).

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery.

Peter Tonzi, Yandong Yin, Chelsea WT Lee, Eli Rothenberg, and Tony T Huang.

eLife 11 13;7 (2018).

Novel Imaging Techniques in Cardiac Ion Channel Research.

Esperanza Agullo-Pascual, Alejandra Leo-Macias, Donna R. Whelan, Mario Delmar, and Eli Rothenberg.

In: Thomas D., Remme C. (eds) Channelopathies in Heart Disease.

Cardiac and Vascular Biology Springer, Cham (2018).

Spatiotemporal Dynamics of Homologous Recombination Repair at Single Collapsed Replication Forks.

Donna Whelan, Wei Ting Chelsea Lee, Yandong Yin, Dylan Ofri, Keria Bermudez-Hernandez, Sarah Keegan, David Fenyö
and Eli Rothenberg.

Nature Communications 9(1):3882 (2018).

XLF and APLF bind to Ku80 on two remote sites to ensure DNA repair by non-homologous end-joining.

Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guérois, Aurelien Pitois, Audrey Comte, Christine Delteil, Nadia Barboule, Pierre Legrand, Sonia Baconnais, Yandong Yin, Satish Tadi,
Emeline Barbet-Massin, Imre Berger, Eric Le Cam, Mauro Modesti, Eli Rothenberg, Patrick Calsou, and Jean-Baptiste Charbonnier.

Nature Structural and Molecular Biology (10):971-980 (2018).

Anosmin1 Shuttles Fgf to Facilitate Its Diffusion, Increase Its Local Concentration, and Induce Sensory Organs.

Wang J, Yin Y, Lau S, Sankaran J, Rothenberg E, Wohland T, Meier-Schellersheim M, Knaut H.

Developmental Cell 46(6):751-766.e12 (2018).

PARP1-Dependent Recruitment of the FBXL10-RNF68-RNF2 Ubiquitin Ligase to
Sites of DNA Damage Controls H2A.Z Loading.

Rona G, Roberti D, Yin Y, Pagan JK, Homer H, Sassani E, Zeke A, Busino L, Rothenberg E, Pagano M.

eLife Jul 9 (2018).

Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors is Required for Cardiomyocyte Integrity in Load-Induced Ventricular Hypertrophy.

Trembley MA, Quijada P, Agullo-Pascual E, Tylock KM, Colpan M, Dirkx RA Jr, Myers JR, Mickelsen DM,

de Mesy Bentley K, Rothenberg E, Moravec CS, Alexis JD, Gregorio CC, Dirksen RT, Delmar M, Small EM.

Circulation May 1. pii. (2018).

The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation
at Sites of DNA Damage, Facilitating Double-Strand Break Repair.

Baranes-Bachar K, Levy-Barda A, Oehler J, Reid DA, Soria-Bretones I, Voss TC, Chung D, Park Y, Liu C, Yoon JB, Li W,
Dellaire G, Misteli T, Huertas P, Rothenberg E, Ramadan K, Ziv Y, Shiloh Y.

Molecular Cell 69(5):866-878 (2018) .

Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment.

Berger SL, Leo-Macias A, Yuen S, Khatri L, Pfennig S, Zhang Y, Agullo-Pascual E, Caillol G, Zhu MS, Rothenberg E, Melendez-Vasquez CV, Delmar M, Leterrier C, Salzer JL.

Neuron 97(3):555-570.e6 (2018).

2017

Sodium Channel Remodeling in Subcellular Microdomains of Murine Failing Cardiomyocytes.

Rivaud MR, Agullo-Pascual E, Lin X, Leo-Macias A, Zhang M, Rothenberg E, Bezzina CR, Delmar M, Remme CA.

Journal of the American Heart Association 6(12) (2017).

A Method for Quantifying Molecular Interactions Using Stochastic Modeling
and Super-Resolution Microscopy.

Keria Bermudez-Hernandez, Sarah Keegan, Donna R. Whelan DR, Dylan A. Reid, Jennifer Zagelbaum,
Yandong Yin, Sisi Ma, Eli Rothenberg*, David Fenyö*.

Scientific Reports 7(1):14882 (2017).

PMID: 29093506.

DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining.

Michael P. Conlin, Dylan A. Reid, George W. Small, Howard H. Chang, Go Watanabe, Michael R. Lieber,
Dale A. Ramsden*, Eli Rothenberg*.

Cell Reports 20(12):2810-2819 (2017).

PMID: 28930678.

Plakophilin-2 is Required for Transcription of Genes that Control Calcium Cycling
and Cardiac Rhythm.

M Cerrone, J Montnach, X Lin X, YT Zhao, M Zhang, E Agullo-Pascual, A Leo-Macias, FJ Alvarado, I Dolgalev,
TV Karathanos, K Malkani, CJM Van Opbergen, JJA van Bavel, HQ Yang, C Vasquez, D Tester, S Fowler, F Liang,
E Rothenberg, A Heguy, GE Morley, WA Coetzee, NA Trayanova, MJ Ackerman, TB van Veen, HH Valdivia,
M Delmar.
Nature Communications 8(1):106 (2017).

PMID: 28740174.

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

W Daddacha, AE Koyen, AJ Bastien, PE Head, VR Dhere, GN Nabeta, EC Connolly, E Werner, MZ Madden, MB Daly, EV Minten, DR Whelan, AJ Schlafstein, H Zhang, R Anand, C Doronio, AE Withers, C Shepard, RK Sundaram, X Deng, WS Dynan, Y Wang, RS Bindra, P Cejka, E Rothenberg, PW Doetsch, B Kim, David S Yu.

Cell Reports 20(8):1921-1935 (2017).

PMID: 28834754.

Multilevel Analyses of SCN5A Mutations in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy suggest Non-Canonical Mechanisms for Disease Pathogenesis.

Te Riele AS, Agullo-Pascual E, James CA, Leo-Macias A, Cerrone M, Zhang M, Lin X, Lin B, Rothenberg E, Sobreira NL, Amat-Alarcon N, Marsman RF, Murray B, Tichnell C, van der Heijden JF, Dooijes D, van Veen TA, Tandri H, Fowler SJ, Hauer RN, Tomaselli G, van den Berg MP, Taylor MR, Brun F, Sinagra G, Wilde AA,
Mestroni L, Bezzina CR, Calkins H, Peter van Tintelen J, Bu L, Delmar M, Judge DP.

Cardiovascular Research 113(1):102-111 (2017).

PMID: 28069705.

Bridging of Double-Stranded Breaks by the Nonhomologous End-Joining Ligation Complex is Modulated by DNA End Chemistry.

Dylan A. Reid, Michael Conlin, Yandong Yin, Howard Chang, Go Watanabe, Michael Lieber*, Dale Ramsden*,
and Eli Rothenberg*.

Nucleic Acid Research 45(4):1872-1878 (2017).

PMID:27924007.

2016

Real-time Analysis of RAG Complex Activity in V(D)J Recombination.

Jennifer Zagelbaum, Noriko Shimazaki , Zitadel Anne Esguerra , Go Watanabe , Michael R Lieber*,
and Eli Rothenberg*.
PNAS 113:11853-11858 (2016).

PMID:27702897.

Probing the Spatial Organization of Molecular Complexes Using Triple-Pair-Correlation.

Yandong Yin, and Eli Rothenberg.

Scientific Reports 22, 6:30819 (2016).

PMID:27545293.

Single Molecule Localization Microscopy of DNA Damage Response Pathways in Cancer.

Donna R. Whelan, Yandong Yin, Keria Bermudez-Hernandez, Sarah Keegan, David Fenyö, and Eli Rothenberg.
Microscopy and Microanalysis 22, S3, 1016-1017 (2016).

The Tumor-Associated Variant RAD51 G151D Induces a Hyper-recombination Phenotype.

Carolyn Marsden, Ryan B. Jensen, Jennifer Zagelbaum, Eli Rothenberg, Scott W Morrical, Susan S Wallace,
and Joann B Sweasy.

PLoS Genetics 11, 12(8): e1006208 (2016).

PMID:27513445.

Nanoscale Visualization of Functional Adhesion/Excitability Nodes at the Intercalated Disc.

Alejandra Leo-Macias, Esperanza Agullo-Pascual, Jose L. Sanchez-Alonso, Sarah Keegan, Xianming Lin,
Tatiana Arcos, Feng-Xia-Liang, Yuri E. Korchev, Julia Gorelik, David Fenyo, Eli Rothenberg*, and Mario Delmar*.
Nature Communications 7:10342 (2016).

PMID:26787348.

2015

TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and
Plays a Role in the DNA Damage Response.

Lauren M. Young, Antonio Marzio, Pablo Perez-Duran, Dylan A. Reid, Daniel N. Meredith, Domenico Roberti, Ayelet Star, Eli Rothenberg, Beatrix Ueberheide, and Michele Pagano.

Cell Reports 15, S2211-1247 (2015).

PMID:26456830.

Repair of Chromosomal Breaks by NHEJ.

Dylan A. Reid, and Eli Rothenberg.

Oncotarget 18, 15730-1 (2015).

PMID:26119149.

Organization and Dynamics of the Nonhomologous End Joining Machinery During
DNA Double Strand Break Repair.

Dylan A. Reid, Sarah Keegan, Alejandra Leo-Macias, Go Watanabe, Natasha T. Strande, Howard H. Chang,
Betul Akgol Oksuz, David Fenyö, Michael Lieber, Dale Ramsden, and Eli Rothenberg.

PNAS 112, 2575-84 (2015).

PMID:25941401.

Recommended by Faculty of 1000 (READ IT HERE)

Single-Molecule Fluorescence Imaging Techniques.

Dylan A. Reid, and Eli Rothenberg.

Encyclopedia of Analytical Chemistry eds R.A. Meyers, John Wiley: Chichester. (2015).

DOI: 10.1002/9780470027318.a9494.

ATR-Mediated Phosphorylation of FANCI Regulates Dormant Origin Firing in Response to Replication Stress.

Yu-Hung Chen, Mathew JK Jones, Yandong Yin, Sarah B. Crist, Luca Colnaghi, Robert J. Sims, Eli Rothenberg, Prasad V. Jallepalli, and Tony T. Huang.

Molecular Cell 58, 323-38 (2015).

PMID: 25843623.

Recommended by Faculty of 1000 (READ IT HERE)

2014

Mechanistic Insight into the Interaction of BLM Helicase with Intra-strand G-quadruplex Structures.

Sujoy Chatterjee, Jennifer Zagelbaum, Pavel Savitsky, Diana Huttner, Pavel Janscak, Ian Hickson, Opher Gileadi, and Eli Rothenberg.

Nature Communications 5:5556 (2014).

Super-Resolution Imaging Reveals that Loss of the C-terminus of Connexin43
Limits Microtubule Plus-end Capture and NaV1.5 Localization at the Intercalated Disc.

Esperanza Agullo-Pascual, Xianming Lin, Alejandra Leo-Macias, Mingliang Zhang, Feng-Xia Liang, Zhen Li,
Anna Pfenniger, Indra Lübkemeier, Sarah Keegan, David Fenyö, Klaus Willecke, Eli Rothenberg, and Mario Delmar.

Cardiovascular Research 104(2):371-81 (2014).

Missense Mutations in Plakophilin-2 Cause Sodium Current Deficit and Associate with a Brugada Syndrome Phenotype.

Marina Cerrone, Xianming Lin, Mingliang Zhang, Esperanza Agullo-Pascual, Anna Pfenniger, Halina Chkourko Gusky, Valeria Novelli, Changsung Kim, Tiara Tirasawasdichai, Daniel P. Judge, Eli Rothenberg, Huei-Sheng Vincent Chen, Carlo Napolitano, Silvia Priori, and Mario Delmar.

Circulation 129(10):1092-103 (2014).

2013

FBH1 Disrupts RAD51 Filaments In Vitro and Modulates Homologous Recombination
in Mammalian Cells.

Jitka Simandlova, Jennifer Zagelbaum, Miranda J. Payne, Wai Kit Chu, Igor Shevelev, Katsuhiro Hanada,
Sujoy Chatterjee, Dylan A. Reid, Ying Liu, Pavel Janscak*, Eli Rothenberg*, and Ian D. Hickson*.

Journal of Biological Chemistry 288, 34168-34180 (2013).

Inhibitors of SCF-Skp2/Cks1 E3 Ligase Block Estrogen-induced Growth Stimulation
and Degradation of Nuclear p27kip1: Therapeutic Potential for Endometrial Cancer.

Savvas C Pavlides, Kuang-Tzu Huang, Dylan A. Reid, Lily Wu, Stephanie V Blank, Khushbakhat Mittal,
Paraskevi Briasouli, Eli Rothenberg*, Bo Rueda*, Timothy Cardozo*, and Leslie I Gold*.

Endocrinology 11, 4030–4045 (2013).

Super-Resolution Fluorescence Microscopy of the Cardiac Connexome Reveals
Plakophilin-2 inside the Connexin43 Plaque.

Esperanza Agullo-Pascual, Dylan A Reid, Sarah Keegan, Manavjeet Sidhu, David Fenyö*, Eli Rothenberg*,

and Mario Delmar*.

Cardiovascular Research 100, 231–240 (2013).

Changes in Psp Protein Binding Partners, Localization and Behavior upon Activation
of the Yersinia enterocolitica Phage Shock Protein Response.

Saori Yamaguchi, Dylan A. Reid, Eli Rothenberg*, and Andrew Darwin*.

Molecular Microbiology 87, 656-671 (2013).

2012

Interaction of Bacteriophage λ with its E. coli Receptor, LamB.

Sujoy Chatterjee, and Eli Rothenberg.

Viruses 4, 3162-3178 (2012).

Heterogeneity of ATP-Sensitive K+ Channels in Cardiac Myocytes: Enrichment
at the Intercalated Disk.

M Hong, Li Bao, Esperanza Agullo-Pascual, E Kefaloyianni, Halina Chkouro, M Foster, E Taskin, M Zhandre,
Dylan A Reid, Eli Rothenberg, Mario Delmar, and William A Coetzee.

Journal of Biological Chemistry 49, 41258-67 (2012).

Remodeling of Mechanical Junctions and of Microtubule-Associated Proteins
Accompany Cardiac Connexin43 Lateralization.

Halina Chkourko, Guadalipe Guerrero-Serna, Xianming Lin, Nedal Darwish, Joshua Pohlmann, Keith Cook, Jeffrey Martens, Eli Rothenberg, Hassan Musa, and Mario Delmar.

Heart Rhythm 9, 1133-1140 (2012).

2011 >

Single-Molecule-Based Super-Resolution Images in the Presence of Multiple Fluorophores.

Paul Simonson, Eli Rothenberg, and Paul Selvin.

Nano Letters 11, 5090-6 (2011).

Two-Photon 3D FIONA of Aqueous Individual Quantum Dots.

Ruobing Zhang*, Eli Rothenberg*, Gilbert Fruhwirth, Paul Simonson, Fangfu Ye, Ido Golding, Tony Ng,
Ward Lopes, and Paul Selvin.

Nano Letters 10, 4074-8 (2011).

Single-Virus Tracking Reveals a Spatial Receptor-Dependent Search Mechanism.

Eli Rothenberg*, Leonardo A. Sepulveda, Samuel O. Skinner, Lanying Zeng, Paul R. Selvin, and Ido Golding.
Biophysical Journal 100, 2875-82 (2011).

Recommended by Faculty of 1000 (READ IT HERE)

Single Molecule FRET Analysis of Helicase Functions.

Eli Rothenberg* and Taekjip Ha.

Methods in Molecular Biology 587, 29-43 (2010).

Human Rad52 Binds and Wraps Single-Stranded DNA and Mediates Annealing
Via Two hRad52-ssDNA Complexes.

Jill M. Grimme, M. Honda, Rebecca Wright, Y. Okuno, Eli Rothenberg, Alex V. Mazin, Taekjip Ha, and Maria Spies.
Nucleic Acid Research 38, 2917-30 (2010).